A pancreatic islet cell tumour is a tumour that develops in the pancreas from a type of cell called an islet cell. It is a rare tumour of the pancreas that starts from the islet cell.

Islet cells manufacture and release hormones, such as insulin and glucagon, into the bloodstream. An islet cell tumour can be benign (noncancerous) or malignant (cancerous).

Like pancreatic adenocarcinoma, islet cell tumours may cause abdominal pain, weight loss, nausea, and vomiting. Islet cell tumour is an older name for pancreatic neuroendocrine tumour (PNET), a type tumour of the pancreas.

Hormones released by an islet cell tumour can also cause symptoms that include: Insulinomas (excess insulin), Glucagonomas (excess glucagon), Gastrinomas (excess gastrin), Somatostatinomas (excess somatostatin), VIPomas (excess vasoactive intestinal peptide).

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